藥物交互作用
Atezolizumab + Piperacillin-tazobactam
嚴重程度: 輕微
Atezolizumab and Piperacillin-tazobactam: minor interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Observational data link antibiotic exposure around the start of immune checkpoint inhibitor therapy with poorer outcomes, possibly through gut microbiome disruption. The evidence is associative and confounded by patient illness severity. The effect on any individual patient is uncertain.
用白話說明這項交互作用的意義
Atezolizumab and Piperacillin-tazobactam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atezolizumab belongs to Oncology; Piperacillin-tazobactam belongs to Anti Bacterial.
為什麼會發生
Proposed disruption of gut microbiota that may modulate antitumor immune response; not firmly established.
處置方式
Use the antibiotic only for a clear indication and de-escalate or stop as soon as culture results and clinical status allow. Do not withhold needed antibiotics.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Piperacillin-tazobactam 的其他交互作用
Atezolizumab 的其他交互作用
常見問題
Can I take Atezolizumab with Piperacillin-tazobactam?
MediHelp rates the interaction as minor. Atezolizumab and Piperacillin-tazobactam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Observational data link antibiotic exposure around the start of immune checkpoint inhibitor therapy with poorer outcomes, possibly through gut microbiome disruption. The evidence is associative and confounded by patient illness severity. The effect on any individual patient is uncertain.
How serious is the interaction between Atezolizumab and Piperacillin-tazobactam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the antibiotic only for a clear indication and de-escalate or stop as soon as culture results and clinical status allow. Do not withhold needed antibiotics.
What other medicines interact with Piperacillin-tazobactam?
MediHelp also lists interactions of Piperacillin-tazobactam with, for example, Vancomycin, Amikacin, Antithrombin alfa. The full list is on the Piperacillin-tazobactam page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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