藥物交互作用
Cefalexin + Gentamicin
嚴重程度: 中度
Cefalexin and Gentamicin: moderate interaction.
最後更新
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摘要
Gentamicin is nephrotoxic and ototoxic, and cephalosporins have been reported to add to renal injury in some patients. Cefalexin is rarely nephrotoxic, so the effect is modest. Risk rises with renal impairment, advanced age, and dehydration.
用白話說明這項交互作用的意義
Cefalexin and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefalexin belongs to Anti Bacterial; Gentamicin belongs to Anti Bacterial.
為什麼會發生
Possible additive nephrotoxicity; mechanism poorly defined.
處置方式
Monitor serum creatinine and gentamicin levels during therapy. Maintain hydration and avoid additional nephrotoxins.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cefalexin 的其他交互作用
Gentamicin 的其他交互作用
常見問題
Can I take Cefalexin with Gentamicin?
MediHelp rates the interaction as moderate. Cefalexin and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Gentamicin is nephrotoxic and ototoxic, and cephalosporins have been reported to add to renal injury in some patients. Cefalexin is rarely nephrotoxic, so the effect is modest. Risk rises with renal impairment, advanced age, and dehydration.
How serious is the interaction between Cefalexin and Gentamicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and gentamicin levels during therapy. Maintain hydration and avoid additional nephrotoxins.
What other medicines interact with Cefalexin?
MediHelp also lists interactions of Cefalexin with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefalexin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
