藥物交互作用
Avanafil + Clarithromycin
嚴重程度: 禁忌併用
Avanafil and Clarithromycin: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Clarithromycin is a strong CYP3A4 inhibitor and markedly increases avanafil exposure. Hypotension, priapism and cardiovascular events are more likely.
用白話說明這項交互作用的意義
Avanafil and Clarithromycin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Avanafil belongs to Genitourinary; Clarithromycin belongs to Anti Bacterial.
為什麼會發生
Strong CYP3A4 inhibition increases avanafil exposure
處置方式
Do not use together; choose a different PDE5 inhibitor or antimicrobial.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Avanafil 的其他交互作用
Clarithromycin 的其他交互作用
常見問題
Can I take Avanafil with Clarithromycin?
MediHelp rates the interaction as contraindicated. Avanafil and Clarithromycin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Clarithromycin is a strong CYP3A4 inhibitor and markedly increases avanafil exposure. Hypotension, priapism and cardiovascular events are more likely.
How serious is the interaction between Avanafil and Clarithromycin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; choose a different PDE5 inhibitor or antimicrobial.
What other medicines interact with Avanafil?
MediHelp also lists interactions of Avanafil with, for example, Amyl nitrite, Atazanavir, Conivaptan. The full list is on the Avanafil page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
