藥物交互作用
Bacitracin + Vancomycin
嚴重程度: 嚴重
Bacitracin and Vancomycin: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Both drugs can injure the kidney, and systemic bacitracin in particular causes dose-related renal tubular damage. Giving them together, especially when vancomycin is parenteral, raises the risk of acute kidney injury, and ototoxicity from vancomycin may add to the concern.
用白話說明這項交互作用的意義
Bacitracin and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bacitracin belongs to Miscellaneous; Vancomycin belongs to Anti Bacterial.
為什麼會發生
Additive nephrotoxicity from two agents that each damage renal tubular cells.
處置方式
Avoid systemic bacitracin with vancomycin; if unavoidable, monitor serum creatinine and urine output frequently and adjust doses to renal function and vancomycin levels.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Vancomycin 的其他交互作用
Bacitracin 的其他交互作用
常見問題
Can I take Bacitracin with Vancomycin?
MediHelp rates the interaction as major. Bacitracin and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can injure the kidney, and systemic bacitracin in particular causes dose-related renal tubular damage. Giving them together, especially when vancomycin is parenteral, raises the risk of acute kidney injury, and ototoxicity from vancomycin may add to the concern.
How serious is the interaction between Bacitracin and Vancomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic bacitracin with vancomycin; if unavoidable, monitor serum creatinine and urine output frequently and adjust doses to renal function and vancomycin levels.
What other medicines interact with Vancomycin?
MediHelp also lists interactions of Vancomycin with, for example, Amikacin, Capreomycin, Cephaloridine. The full list is on the Vancomycin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
