藥物交互作用
Cidofovir + Vancomycin
嚴重程度: 嚴重
Cidofovir and Vancomycin: major interaction.
最後更新
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摘要
Both drugs can injure the kidney, and combined use may raise the risk of acute kidney injury. Cidofovir carries a boxed warning for renal toxicity and its label advises against use with other nephrotoxic agents.
用白話說明這項交互作用的意義
Cidofovir and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cidofovir belongs to Anti Virals; Vancomycin belongs to Anti Bacterial.
為什麼會發生
Additive nephrotoxicity, with cidofovir causing proximal tubular injury and vancomycin contributing tubular toxicity.
處置方式
Avoid concurrent use where possible; if unavoidable, ensure hydration with probenecid per cidofovir protocol and monitor serum creatinine and urinalysis before each cidofovir dose. Consider alternatives to vancomycin.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Vancomycin 的其他交互作用
Cidofovir 的其他交互作用
常見問題
Can I take Cidofovir with Vancomycin?
MediHelp rates the interaction as major. Cidofovir and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can injure the kidney, and combined use may raise the risk of acute kidney injury. Cidofovir carries a boxed warning for renal toxicity and its label advises against use with other nephrotoxic agents.
How serious is the interaction between Cidofovir and Vancomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where possible; if unavoidable, ensure hydration with probenecid per cidofovir protocol and monitor serum creatinine and urinalysis before each cidofovir dose. Consider alternatives to vancomycin.
What other medicines interact with Vancomycin?
MediHelp also lists interactions of Vancomycin with, for example, Amikacin, Bacitracin, Capreomycin. The full list is on the Vancomycin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
