藥物交互作用
Bacitracin-neomycin-polymyxin + Capreomycin
嚴重程度: 嚴重
Bacitracin-neomycin-polymyxin and Capreomycin: major interaction.
最後更新
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摘要
Capreomycin is nephrotoxic and ototoxic, and neomycin and polymyxin B carry the same risks when absorbed. Combining them can cause additive kidney injury, hearing loss and neuromuscular blockade, especially with large-surface or irrigation use.
用白話說明這項交互作用的意義
Bacitracin-neomycin-polymyxin and Capreomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive nephrotoxicity, ototoxicity and neuromuscular blockade from drugs with overlapping toxicity.
處置方式
Avoid concurrent systemic or high-absorption use of these agents. If unavoidable, monitor serum creatinine, electrolytes and hearing, and use the shortest possible course.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Bacitracin-neomycin-polymyxin 的其他交互作用
- Allogeneic cultured keratinocytes / fibroblasts in bovine collagen + Bacitracin-neomycin-polymyxin 嚴重
- Atracurium + Bacitracin-neomycin-polymyxin 嚴重
- Bacitracin-neomycin-polymyxin + Cidofovir 嚴重
- Bacitracin-neomycin-polymyxin + Cisatracurium 嚴重
- Bacitracin-neomycin-polymyxin + Pancuronium 嚴重
- Bacitracin-neomycin-polymyxin + Rocuronium 嚴重
常見問題
Can I take Bacitracin-neomycin-polymyxin with Capreomycin?
MediHelp rates the interaction as major. Bacitracin-neomycin-polymyxin and Capreomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Capreomycin is nephrotoxic and ototoxic, and neomycin and polymyxin B carry the same risks when absorbed. Combining them can cause additive kidney injury, hearing loss and neuromuscular blockade, especially with large-surface or irrigation use.
How serious is the interaction between Bacitracin-neomycin-polymyxin and Capreomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent systemic or high-absorption use of these agents. If unavoidable, monitor serum creatinine, electrolytes and hearing, and use the shortest possible course.
What other medicines interact with Bacitracin-neomycin-polymyxin?
MediHelp also lists interactions of Bacitracin-neomycin-polymyxin with, for example, Allogeneic cultured keratinocytes / fibroblasts in bovine collagen, Atracurium, Cidofovir. The full list is on the Bacitracin-neomycin-polymyxin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
