藥物交互作用
Bacitracin-neomycin-polymyxin + Cidofovir
嚴重程度: 嚴重
Bacitracin-neomycin-polymyxin and Cidofovir: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Systemic polymyxin B, neomycin and bacitracin are nephrotoxic, and cidofovir causes dose-limiting proximal tubular kidney injury. Combined exposure may cause severe renal damage, and cidofovir labeling contraindicates concurrent nephrotoxic agents. Risk applies mainly to systemic or heavily absorbed use rather than small topical applications.
用白話說明這項交互作用的意義
Bacitracin-neomycin-polymyxin and Cidofovir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bacitracin-neomycin-polymyxin belongs to Anti Bacterial; Cidofovir belongs to Anti Virals.
為什麼會發生
Additive nephrotoxicity through direct renal tubular injury by both agents.
處置方式
Avoid systemic or heavily absorbed use of these antibiotics during and shortly after cidofovir therapy. If unavoidable, monitor serum creatinine and urine protein closely.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Bacitracin-neomycin-polymyxin 的其他交互作用
- Allogeneic cultured keratinocytes / fibroblasts in bovine collagen + Bacitracin-neomycin-polymyxin 嚴重
- Atracurium + Bacitracin-neomycin-polymyxin 嚴重
- Bacitracin-neomycin-polymyxin + Capreomycin 嚴重
- Bacitracin-neomycin-polymyxin + Cisatracurium 嚴重
- Bacitracin-neomycin-polymyxin + Pancuronium 嚴重
- Bacitracin-neomycin-polymyxin + Rocuronium 嚴重
Cidofovir 的其他交互作用
常見問題
Can I take Bacitracin-neomycin-polymyxin with Cidofovir?
MediHelp rates the interaction as major. Bacitracin-neomycin-polymyxin and Cidofovir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Systemic polymyxin B, neomycin and bacitracin are nephrotoxic, and cidofovir causes dose-limiting proximal tubular kidney injury. Combined exposure may cause severe renal damage, and cidofovir labeling contraindicates concurrent nephrotoxic agents. Risk applies mainly to systemic or heavily absorbed use rather than small topical applications.
How serious is the interaction between Bacitracin-neomycin-polymyxin and Cidofovir?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic or heavily absorbed use of these antibiotics during and shortly after cidofovir therapy. If unavoidable, monitor serum creatinine and urine protein closely.
What other medicines interact with Bacitracin-neomycin-polymyxin?
MediHelp also lists interactions of Bacitracin-neomycin-polymyxin with, for example, Allogeneic cultured keratinocytes / fibroblasts in bovine collagen, Atracurium, Capreomycin. The full list is on the Bacitracin-neomycin-polymyxin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
