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藥物交互作用

Baloxavir marboxil + Zinc

嚴重程度: 中度

Baloxavir marboxil and Zinc: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Zinc supplements can bind baloxavir in the gut and reduce its absorption. This may lower antiviral concentrations and diminish efficacy against influenza.

用白話說明這項交互作用的意義

Baloxavir marboxil and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Baloxavir marboxil belongs to Anti Virals; Zinc belongs to Gastrointestinal Tract.

證據等級: Moderate

為什麼會發生

Polyvalent zinc cations chelate baloxavir in the gastrointestinal tract, reducing absorption.

處置方式

Avoid taking zinc-containing products with baloxavir and defer them until after the antiviral course where feasible. If they must be used, separate dosing as widely as practical.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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常見問題

Can I take Baloxavir marboxil with Zinc?

MediHelp rates the interaction as moderate. Baloxavir marboxil and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Zinc supplements can bind baloxavir in the gut and reduce its absorption. This may lower antiviral concentrations and diminish efficacy against influenza.

How serious is the interaction between Baloxavir marboxil and Zinc?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid taking zinc-containing products with baloxavir and defer them until after the antiviral course where feasible. If they must be used, separate dosing as widely as practical.

What other medicines interact with Baloxavir marboxil?

MediHelp also lists interactions of Baloxavir marboxil with, for example, Aluminum hydroxide, Calcium, Calcium carbonate. The full list is on the Baloxavir marboxil page.

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