藥物交互作用
Delafloxacin + Zinc
嚴重程度: 中度
Delafloxacin and Zinc: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Zinc binds oral delafloxacin in the gut and reduces its absorption, potentially causing subtherapeutic antibiotic levels and treatment failure.
用白話說明這項交互作用的意義
Delafloxacin and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Delafloxacin belongs to Anti Bacterial; Zinc belongs to Gastrointestinal Tract.
為什麼會發生
Chelation of delafloxacin by polyvalent metal cations reduces gastrointestinal absorption.
處置方式
Take delafloxacin at least 2 hours before or 6 hours after zinc products. Consider the intravenous formulation if separation is not possible.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Delafloxacin 的其他交互作用
Zinc 的其他交互作用
常見問題
Can I take Delafloxacin with Zinc?
MediHelp rates the interaction as moderate. Delafloxacin and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Zinc binds oral delafloxacin in the gut and reduces its absorption, potentially causing subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Delafloxacin and Zinc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take delafloxacin at least 2 hours before or 6 hours after zinc products. Consider the intravenous formulation if separation is not possible.
What other medicines interact with Delafloxacin?
MediHelp also lists interactions of Delafloxacin with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Delafloxacin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。