藥物交互作用
Ciprofloxacin + Zinc
嚴重程度: 中度
Ciprofloxacin and Zinc: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Zinc binds ciprofloxacin in the gut and markedly reduces its absorption, which can lead to subtherapeutic antibiotic levels and treatment failure.
用白話說明這項交互作用的意義
Ciprofloxacin and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ciprofloxacin belongs to Anti Bacterial; Zinc belongs to Gastrointestinal Tract.
為什麼會發生
Chelation of ciprofloxacin by divalent zinc cations in the gastrointestinal tract, forming poorly absorbed complexes.
處置方式
Give ciprofloxacin at least 2 hours before or 6 hours after zinc-containing products. Counsel patients about multivitamins and mineral supplements.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Ciprofloxacin 的其他交互作用
Zinc 的其他交互作用
常見問題
Can I take Ciprofloxacin with Zinc?
MediHelp rates the interaction as moderate. Ciprofloxacin and Zinc can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Zinc binds ciprofloxacin in the gut and markedly reduces its absorption, which can lead to subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Ciprofloxacin and Zinc?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give ciprofloxacin at least 2 hours before or 6 hours after zinc-containing products. Counsel patients about multivitamins and mineral supplements.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
