藥物交互作用
Bcg vaccine live + Budesonide
嚴重程度: 嚴重
Bcg vaccine live and Budesonide: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Live BCG given during corticosteroid-induced immunosuppression may cause disseminated BCG infection and be less effective. Risk is greatest with systemic budesonide or high-dose therapy; low-dose inhaled or topical-acting use is less of a concern.
用白話說明這項交互作用的意義
Bcg vaccine live and Budesonide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Corticosteroid suppression of cell-mediated immunity impairs control of live attenuated mycobacteria.
處置方式
Avoid live BCG in patients receiving immunosuppressive doses of budesonide; defer vaccination until steroids are stopped for the labeled interval.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Budesonide 的其他交互作用
常見問題
Can I take Bcg vaccine live with Budesonide?
MediHelp rates the interaction as major. Bcg vaccine live and Budesonide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Live BCG given during corticosteroid-induced immunosuppression may cause disseminated BCG infection and be less effective. Risk is greatest with systemic budesonide or high-dose therapy; low-dose inhaled or topical-acting use is less of a concern.
How serious is the interaction between Bcg vaccine live and Budesonide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live BCG in patients receiving immunosuppressive doses of budesonide; defer vaccination until steroids are stopped for the labeled interval.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Ceritinib. The full list is on the Budesonide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
