藥物交互作用
Bcg vaccine live + Chloramphenicol
嚴重程度: 嚴重
Bcg vaccine live and Chloramphenicol: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Chloramphenicol is active against many bacteria and may reduce the replication of the live attenuated bacteria in the vaccine. This can lead to a weaker immune response and reduced protection.
用白話說明這項交互作用的意義
Bcg vaccine live and Chloramphenicol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Antibacterial activity of chloramphenicol may inhibit the live attenuated bacterial vaccine strain, reducing immunogenicity.
處置方式
Defer the live BCG vaccination until the chloramphenicol course is finished, allowing an adequate washout interval. Revaccinate if the vaccine was given during antibiotic therapy.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Chloramphenicol 的其他交互作用
常見問題
Can I take Bcg vaccine live with Chloramphenicol?
MediHelp rates the interaction as major. Bcg vaccine live and Chloramphenicol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Chloramphenicol is active against many bacteria and may reduce the replication of the live attenuated bacteria in the vaccine. This can lead to a weaker immune response and reduced protection.
How serious is the interaction between Bcg vaccine live and Chloramphenicol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Defer the live BCG vaccination until the chloramphenicol course is finished, allowing an adequate washout interval. Revaccinate if the vaccine was given during antibiotic therapy.
What other medicines interact with Chloramphenicol?
MediHelp also lists interactions of Chloramphenicol with, for example, Adagrasib, Avapritinib, Benzhydrocodone / acetaminophen. The full list is on the Chloramphenicol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
