藥物交互作用
Bendroflumethiazide + Calcium
嚴重程度: 中度
Bendroflumethiazide and Calcium: moderate interaction.
最後更新
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摘要
Thiazide diuretics reduce urinary calcium excretion, so adding calcium supplements can raise serum calcium. Hypercalcemia and, with alkali co-ingestion, milk-alkali syndrome may occur, especially with high calcium doses or renal impairment.
用白話說明這項交互作用的意義
Bendroflumethiazide and Calcium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Thiazides increase distal tubular calcium reabsorption, decreasing renal calcium clearance.
處置方式
Monitor serum calcium periodically, particularly when starting or increasing calcium or vitamin D. Reduce the calcium dose if hypercalcemia develops.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Calcium 的其他交互作用
常見問題
Can I take Bendroflumethiazide with Calcium?
MediHelp rates the interaction as moderate. Bendroflumethiazide and Calcium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thiazide diuretics reduce urinary calcium excretion, so adding calcium supplements can raise serum calcium. Hypercalcemia and, with alkali co-ingestion, milk-alkali syndrome may occur, especially with high calcium doses or renal impairment.
How serious is the interaction between Bendroflumethiazide and Calcium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium periodically, particularly when starting or increasing calcium or vitamin D. Reduce the calcium dose if hypercalcemia develops.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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