藥物交互作用
Benzphetamine + Isocarboxazid
嚴重程度: 禁忌併用
Benzphetamine and Isocarboxazid: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Benzphetamine is a sympathomimetic, and with an MAOI it can provoke severe hypertension and hypertensive crisis. It is contraindicated during and shortly after MAOI therapy.
用白話說明這項交互作用的意義
Benzphetamine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
MAO inhibition leaves norepinephrine stores increased, and the amphetamine-like release of these stores causes an exaggerated pressor response.
處置方式
Do not use together or within 14 days of stopping the MAOI. Choose non-pharmacologic or non-stimulant weight management options.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Isocarboxazid 的其他交互作用
常見問題
Can I take Benzphetamine with Isocarboxazid?
MediHelp rates the interaction as contraindicated. Benzphetamine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Benzphetamine is a sympathomimetic, and with an MAOI it can provoke severe hypertension and hypertensive crisis. It is contraindicated during and shortly after MAOI therapy.
How serious is the interaction between Benzphetamine and Isocarboxazid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together or within 14 days of stopping the MAOI. Choose non-pharmacologic or non-stimulant weight management options.
What other medicines interact with Isocarboxazid?
MediHelp also lists interactions of Isocarboxazid with, for example, 5-HTP, Amitriptyline, Amobarbital. The full list is on the Isocarboxazid page.
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