藥物交互作用
Bisoprolol + Carvedilol
嚴重程度: 嚴重
Bisoprolol and Carvedilol: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Both are beta-blockers used in heart failure and hypertension, and combining them duplicates therapy. Carvedilol also blocks alpha-1 receptors, so hypotension, bradycardia and AV block may be additive.
用白話說明這項交互作用的意義
Bisoprolol and Carvedilol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bisoprolol belongs to Cardiovascular; Carvedilol belongs to Cardiovascular.
為什麼會發生
Additive beta-adrenergic blockade, with added alpha-1 blockade from carvedilol.
處置方式
Avoid using two beta-blockers together; select one agent and titrate it. If an overlap occurs, stop one and monitor heart rate, blood pressure and signs of heart failure.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Bisoprolol 的其他交互作用
Carvedilol 的其他交互作用
常見問題
Can I take Bisoprolol with Carvedilol?
MediHelp rates the interaction as major. Bisoprolol and Carvedilol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both are beta-blockers used in heart failure and hypertension, and combining them duplicates therapy. Carvedilol also blocks alpha-1 receptors, so hypotension, bradycardia and AV block may be additive.
How serious is the interaction between Bisoprolol and Carvedilol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using two beta-blockers together; select one agent and titrate it. If an overlap occurs, stop one and monitor heart rate, blood pressure and signs of heart failure.
What other medicines interact with Bisoprolol?
MediHelp also lists interactions of Bisoprolol with, for example, Aldesleukin, Amifostine, Amiodarone. The full list is on the Bisoprolol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
