藥物交互作用
Brexpiprazole + Dexbrompheniramine
嚴重程度: 中度
Brexpiprazole and Dexbrompheniramine: moderate interaction.
最後更新
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摘要
Both drugs cause sedation, so taking them together can deepen drowsiness and impair alertness, psychomotor performance and driving ability. The effect is most relevant in older patients and at treatment initiation.
用白話說明這項交互作用的意義
Brexpiprazole and Dexbrompheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brexpiprazole belongs to Central Nervous System; Dexbrompheniramine belongs to Respiratory.
為什麼會發生
Additive CNS depression from antihistaminergic and antipsychotic sedative effects.
處置方式
Warn patients about drowsiness and avoid driving or hazardous tasks until response is known. Prefer a non-sedating antihistamine if one is needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Brexpiprazole 的其他交互作用
Dexbrompheniramine 的其他交互作用
常見問題
Can I take Brexpiprazole with Dexbrompheniramine?
MediHelp rates the interaction as moderate. Brexpiprazole and Dexbrompheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs cause sedation, so taking them together can deepen drowsiness and impair alertness, psychomotor performance and driving ability. The effect is most relevant in older patients and at treatment initiation.
How serious is the interaction between Brexpiprazole and Dexbrompheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Warn patients about drowsiness and avoid driving or hazardous tasks until response is known. Prefer a non-sedating antihistamine if one is needed.
What other medicines interact with Brexpiprazole?
MediHelp also lists interactions of Brexpiprazole with, for example, Alfentanil, Amisulpride, Apalutamide. The full list is on the Brexpiprazole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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