藥物交互作用
Brexpiprazole + Pheniramine
嚴重程度: 中度
Brexpiprazole and Pheniramine: moderate interaction.
最後更新
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摘要
Pheniramine is a sedating first-generation antihistamine, and brexpiprazole is also sedating. Together they may cause pronounced drowsiness and impaired psychomotor performance, and anticholinergic effects may be additive.
用白話說明這項交互作用的意義
Brexpiprazole and Pheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brexpiprazole belongs to Central Nervous System; Pheniramine belongs to Respiratory.
為什麼會發生
Additive CNS depression through histamine H1 receptor antagonism and other receptor blockade.
處置方式
Counsel patients about drowsiness and avoiding driving or hazardous tasks. Prefer a non-sedating antihistamine if one is suitable.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Brexpiprazole 的其他交互作用
Pheniramine 的其他交互作用
常見問題
Can I take Brexpiprazole with Pheniramine?
MediHelp rates the interaction as moderate. Brexpiprazole and Pheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pheniramine is a sedating first-generation antihistamine, and brexpiprazole is also sedating. Together they may cause pronounced drowsiness and impaired psychomotor performance, and anticholinergic effects may be additive.
How serious is the interaction between Brexpiprazole and Pheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about drowsiness and avoiding driving or hazardous tasks. Prefer a non-sedating antihistamine if one is suitable.
What other medicines interact with Brexpiprazole?
MediHelp also lists interactions of Brexpiprazole with, for example, Alfentanil, Amisulpride, Apalutamide. The full list is on the Brexpiprazole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
