藥物交互作用
Butorphanol + Olanzapine / samidorphan
嚴重程度: 禁忌併用
Butorphanol and Olanzapine / samidorphan: contraindicated interaction.
最後更新
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摘要
Samidorphan is an opioid antagonist that blocks butorphanol's analgesic effect. In opioid-dependent patients it may precipitate acute withdrawal.
用白話說明這項交互作用的意義
Butorphanol and Olanzapine / samidorphan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Samidorphan antagonizes opioid receptors, opposing the effect of butorphanol.
處置方式
Avoid the combination; follow the labeled opioid-free interval (7 days for short-acting, 14 days for long-acting opioids) before starting. Use non-opioid analgesics during treatment.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Butorphanol 的其他交互作用
常見問題
Can I take Butorphanol with Olanzapine / samidorphan?
MediHelp rates the interaction as contraindicated. Butorphanol and Olanzapine / samidorphan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Samidorphan is an opioid antagonist that blocks butorphanol's analgesic effect. In opioid-dependent patients it may precipitate acute withdrawal.
How serious is the interaction between Butorphanol and Olanzapine / samidorphan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; follow the labeled opioid-free interval (7 days for short-acting, 14 days for long-acting opioids) before starting. Use non-opioid analgesics during treatment.
What other medicines interact with Butorphanol?
MediHelp also lists interactions of Butorphanol with, for example, Sodium oxybate, Alfentanil, Alprazolam. The full list is on the Butorphanol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
