藥物交互作用
Butorphanol + Sodium oxybate
嚴重程度: 禁忌併用
Butorphanol and Sodium oxybate: contraindicated interaction.
最後更新
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摘要
Both drugs depress the central nervous system, and combining them can cause profound sedation, respiratory depression, coma and death. Labeling for sodium oxybate generally warns against use with other CNS depressants such as opioids.
用白話說明這項交互作用的意義
Butorphanol and Sodium oxybate are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Butorphanol belongs to Musculoskeletal; Sodium oxybate belongs to Central Nervous System.
為什麼會發生
Additive pharmacodynamic CNS and respiratory depression.
處置方式
Avoid the combination. If an opioid is unavoidable, use the lowest dose for the shortest time, and monitor respiratory status and consciousness closely, with consideration of reducing or interrupting oxybate.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Butorphanol 的其他交互作用
Sodium oxybate 的其他交互作用
常見問題
Can I take Butorphanol with Sodium oxybate?
MediHelp rates the interaction as contraindicated. Butorphanol and Sodium oxybate are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs depress the central nervous system, and combining them can cause profound sedation, respiratory depression, coma and death. Labeling for sodium oxybate generally warns against use with other CNS depressants such as opioids.
How serious is the interaction between Butorphanol and Sodium oxybate?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination. If an opioid is unavoidable, use the lowest dose for the shortest time, and monitor respiratory status and consciousness closely, with consideration of reducing or interrupting oxybate.
What other medicines interact with Butorphanol?
MediHelp also lists interactions of Butorphanol with, for example, Olanzapine / samidorphan, Alfentanil, Alprazolam. The full list is on the Butorphanol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
