藥物交互作用
Cidofovir + Gentamicin
嚴重程度: 禁忌併用
Cidofovir and Gentamicin: contraindicated interaction.
最後更新
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摘要
Both drugs injure the proximal renal tubule, so combined use can cause severe acute kidney injury. Cidofovir labeling contraindicates concurrent use with other nephrotoxic agents including aminoglycosides.
用白話說明這項交互作用的意義
Cidofovir and Gentamicin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Cidofovir belongs to Anti Virals; Gentamicin belongs to Anti Bacterial.
為什麼會發生
Additive direct tubular nephrotoxicity.
處置方式
Do not give together; stop the aminoglycoside at least 7 days before starting cidofovir or choose a non-nephrotoxic alternative.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Gentamicin 的其他交互作用
Cidofovir 的其他交互作用
常見問題
Can I take Cidofovir with Gentamicin?
MediHelp rates the interaction as contraindicated. Cidofovir and Gentamicin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs injure the proximal renal tubule, so combined use can cause severe acute kidney injury. Cidofovir labeling contraindicates concurrent use with other nephrotoxic agents including aminoglycosides.
How serious is the interaction between Cidofovir and Gentamicin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give together; stop the aminoglycoside at least 7 days before starting cidofovir or choose a non-nephrotoxic alternative.
What other medicines interact with Gentamicin?
MediHelp also lists interactions of Gentamicin with, for example, Adefovir, Amikacin, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Gentamicin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
