藥物交互作用
Cenobamate + Nevirapine
嚴重程度: 嚴重
Cenobamate and Nevirapine: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Cenobamate is a CYP3A4 and CYP2B6 inducer and may reduce nevirapine concentrations. Lower levels risk virologic failure and resistance.
用白話說明這項交互作用的意義
Cenobamate and Nevirapine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cenobamate belongs to Central Nervous System; Nevirapine belongs to Anti Virals.
為什麼會發生
Cenobamate induces CYP3A4 and CYP2B6, increasing nevirapine clearance.
處置方式
Monitor HIV viral load and nevirapine trough levels if available. Consider an alternative antiretroviral or antiseizure drug.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Nevirapine 的其他交互作用
Cenobamate 的其他交互作用
常見問題
Can I take Cenobamate with Nevirapine?
MediHelp rates the interaction as major. Cenobamate and Nevirapine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cenobamate is a CYP3A4 and CYP2B6 inducer and may reduce nevirapine concentrations. Lower levels risk virologic failure and resistance.
How serious is the interaction between Cenobamate and Nevirapine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor HIV viral load and nevirapine trough levels if available. Consider an alternative antiretroviral or antiseizure drug.
What other medicines interact with Nevirapine?
MediHelp also lists interactions of Nevirapine with, for example, Elbasvir / grazoprevir, Ranolazine, St john's wort. The full list is on the Nevirapine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
