藥物交互作用
Chlorpromazine + Droperidol
嚴重程度: 禁忌併用
Chlorpromazine and Droperidol: contraindicated interaction.
最後更新
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摘要
Both drugs are dopamine antagonists that prolong the QT interval, and droperidol carries a boxed warning for torsades de pointes. Combined use markedly increases arrhythmia risk and additive sedation.
用白話說明這項交互作用的意義
Chlorpromazine and Droperidol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Additive blockade of cardiac potassium channels with QT prolongation, plus additive CNS depression.
處置方式
Avoid using together; select an antiemetic or sedative without QT effects. If unavoidable, use continuous ECG monitoring and correct electrolytes.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Chlorpromazine 的其他交互作用
常見問題
Can I take Chlorpromazine with Droperidol?
MediHelp rates the interaction as contraindicated. Chlorpromazine and Droperidol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs are dopamine antagonists that prolong the QT interval, and droperidol carries a boxed warning for torsades de pointes. Combined use markedly increases arrhythmia risk and additive sedation.
How serious is the interaction between Chlorpromazine and Droperidol?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using together; select an antiemetic or sedative without QT effects. If unavoidable, use continuous ECG monitoring and correct electrolytes.
What other medicines interact with Chlorpromazine?
MediHelp also lists interactions of Chlorpromazine with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Chlorpromazine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
