藥物交互作用
Chlorpromazine + Panobinostat
嚴重程度: 禁忌併用
Chlorpromazine and Panobinostat: contraindicated interaction.
最後更新
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摘要
Panobinostat prolongs the QT interval and chlorpromazine has the same effect, so using both increases the risk of torsade de pointes. Panobinostat labeling advises against use with QT-prolonging drugs.
用白話說明這項交互作用的意義
Chlorpromazine and Panobinostat are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Chlorpromazine belongs to Central Nervous System; Panobinostat belongs to Oncology.
為什麼會發生
Additive QT prolongation through effects on cardiac repolarization.
處置方式
Do not use together; choose an antipsychotic or antiemetic without QT effect. If unavoidable, monitor ECG and electrolytes intensively.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Chlorpromazine 的其他交互作用
Panobinostat 的其他交互作用
常見問題
Can I take Chlorpromazine with Panobinostat?
MediHelp rates the interaction as contraindicated. Chlorpromazine and Panobinostat are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Panobinostat prolongs the QT interval and chlorpromazine has the same effect, so using both increases the risk of torsade de pointes. Panobinostat labeling advises against use with QT-prolonging drugs.
How serious is the interaction between Chlorpromazine and Panobinostat?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; choose an antipsychotic or antiemetic without QT effect. If unavoidable, monitor ECG and electrolytes intensively.
What other medicines interact with Chlorpromazine?
MediHelp also lists interactions of Chlorpromazine with, for example, Dofetilide, Dronedarone, Droperidol. The full list is on the Chlorpromazine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
