藥物交互作用
Chlorpromazine + Pimozide
嚴重程度: 禁忌併用
Chlorpromazine and Pimozide: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Chlorpromazine and pimozide both lengthen the QT interval, and pimozide's narrow safety margin makes any added QT effect dangerous. Torsades de pointes is the principal concern.
用白話說明這項交互作用的意義
Chlorpromazine and Pimozide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Chlorpromazine belongs to Central Nervous System; Pimozide belongs to Central Nervous System.
為什麼會發生
Additive QTc prolongation
處置方式
Do not co-prescribe; use only one antipsychotic.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Chlorpromazine 的其他交互作用
Pimozide 的其他交互作用
常見問題
Can I take Chlorpromazine with Pimozide?
MediHelp rates the interaction as contraindicated. Chlorpromazine and Pimozide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Chlorpromazine and pimozide both lengthen the QT interval, and pimozide's narrow safety margin makes any added QT effect dangerous. Torsades de pointes is the principal concern.
How serious is the interaction between Chlorpromazine and Pimozide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-prescribe; use only one antipsychotic.
What other medicines interact with Chlorpromazine?
MediHelp also lists interactions of Chlorpromazine with, for example, Dofetilide, Dronedarone, Droperidol. The full list is on the Chlorpromazine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
