藥物交互作用
Cholera vaccine + Minocycline
嚴重程度: 嚴重
Cholera vaccine and Minocycline: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
The oral live attenuated cholera vaccine relies on the vaccine strain colonising the gut, and antibiotics active against it can reduce the immune response. Minocycline may therefore make the vaccine less effective.
用白話說明這項交互作用的意義
Cholera vaccine and Minocycline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Antibacterial activity against the live attenuated Vibrio cholerae vaccine strain reduces colonisation and immunogenicity.
處置方式
Do not give the vaccine to patients who have received systemic antibiotics in the preceding 14 days, and avoid antibiotics for a period after vaccination per labeling. Delay vaccination if needed.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Minocycline 的其他交互作用
常見問題
Can I take Cholera vaccine with Minocycline?
MediHelp rates the interaction as major. Cholera vaccine and Minocycline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. The oral live attenuated cholera vaccine relies on the vaccine strain colonising the gut, and antibiotics active against it can reduce the immune response. Minocycline may therefore make the vaccine less effective.
How serious is the interaction between Cholera vaccine and Minocycline?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the vaccine to patients who have received systemic antibiotics in the preceding 14 days, and avoid antibiotics for a period after vaccination per labeling. Delay vaccination if needed.
What other medicines interact with Minocycline?
MediHelp also lists interactions of Minocycline with, for example, Acitretin, Isotretinoin, Methoxyflurane. The full list is on the Minocycline page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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