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藥物交互作用

Isotretinoin + Minocycline

嚴重程度: 禁忌併用

Isotretinoin and Minocycline: contraindicated interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Isotretinoin and tetracyclines such as minocycline can each cause raised intracranial pressure (pseudotumour cerebri). Used together they may lead to headache, visual disturbance and papilloedema.

用白話說明這項交互作用的意義

Isotretinoin and Minocycline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Isotretinoin belongs to Dermatology; Minocycline belongs to Anti Bacterial.

證據等級: Moderate

為什麼會發生

Additive risk of idiopathic intracranial hypertension

處置方式

Avoid combination; use a non-tetracycline antibiotic during isotretinoin therapy and urgently evaluate headache or visual changes.

可向藥師詢問的問題

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Isotretinoin 與 Minocycline 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Isotretinoin with Minocycline?

MediHelp rates the interaction as contraindicated. Isotretinoin and Minocycline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Isotretinoin and tetracyclines such as minocycline can each cause raised intracranial pressure (pseudotumour cerebri). Used together they may lead to headache, visual disturbance and papilloedema.

How serious is the interaction between Isotretinoin and Minocycline?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combination; use a non-tetracycline antibiotic during isotretinoin therapy and urgently evaluate headache or visual changes.

What other medicines interact with Minocycline?

MediHelp also lists interactions of Minocycline with, for example, Acitretin, Cholera vaccine, Methoxyflurane. The full list is on the Minocycline page.

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