藥物交互作用
Minocycline + Strontium ranelate
嚴重程度: 嚴重
Minocycline and Strontium ranelate: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Oral strontium ranelate can bind minocycline in the gut and lower its absorption, risking subtherapeutic antibiotic levels. This applies to oral forms of both drugs.
用白話說明這項交互作用的意義
Minocycline and Strontium ranelate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Minocycline belongs to Anti Bacterial; Strontium ranelate belongs to Musculoskeletal.
為什麼會發生
Chelation by divalent strontium cations in the gastrointestinal tract reduces minocycline absorption.
處置方式
Suspend strontium ranelate during minocycline therapy and restart it after the antibiotic course is complete.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Minocycline 的其他交互作用
Strontium ranelate 的其他交互作用
常見問題
Can I take Minocycline with Strontium ranelate?
MediHelp rates the interaction as major. Minocycline and Strontium ranelate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral strontium ranelate can bind minocycline in the gut and lower its absorption, risking subtherapeutic antibiotic levels. This applies to oral forms of both drugs.
How serious is the interaction between Minocycline and Strontium ranelate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Suspend strontium ranelate during minocycline therapy and restart it after the antibiotic course is complete.
What other medicines interact with Minocycline?
MediHelp also lists interactions of Minocycline with, for example, Acitretin, Isotretinoin, Cholera vaccine. The full list is on the Minocycline page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。