藥物交互作用
Cidofovir + Polymyxin b
嚴重程度: 禁忌併用
Cidofovir and Polymyxin b: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Both drugs injure the renal tubules, and polymyxin B also has neurotoxic effects. Concurrent use greatly increases the risk of acute kidney injury.
用白話說明這項交互作用的意義
Cidofovir and Polymyxin b are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Cidofovir belongs to Anti Virals; Polymyxin b belongs to Anti Bacterial.
為什麼會發生
Additive direct tubular nephrotoxicity.
處置方式
Avoid the combination, as cidofovir labeling prohibits concurrent nephrotoxins. Use an alternative antibiotic or antiviral, and if unavoidable, monitor creatinine daily.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Cidofovir 的其他交互作用
Polymyxin b 的其他交互作用
常見問題
Can I take Cidofovir with Polymyxin b?
MediHelp rates the interaction as contraindicated. Cidofovir and Polymyxin b are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs injure the renal tubules, and polymyxin B also has neurotoxic effects. Concurrent use greatly increases the risk of acute kidney injury.
How serious is the interaction between Cidofovir and Polymyxin b?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination, as cidofovir labeling prohibits concurrent nephrotoxins. Use an alternative antibiotic or antiviral, and if unavoidable, monitor creatinine daily.
What other medicines interact with Cidofovir?
MediHelp also lists interactions of Cidofovir with, for example, Amikacin, Amphotericin b deoxycholate, Amphotericin b. The full list is on the Cidofovir page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
