藥物交互作用
Cisapride + Escitalopram
嚴重程度: 禁忌併用
Cisapride and Escitalopram: contraindicated interaction.
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摘要
Cisapride can cause dose-related torsades de pointes, and escitalopram also prolongs the QT interval in a dose-dependent fashion. The combination is contraindicated in the cisapride labelling.
用白話說明這項交互作用的意義
Cisapride and Escitalopram are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Cisapride belongs to Gastrointestinal Tract; Escitalopram belongs to Central Nervous System.
為什麼會發生
Additive QTc prolongation
處置方式
Do not co-administer; use a prokinetic without QT effect or an alternative antidepressant.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Cisapride 的其他交互作用
Escitalopram 的其他交互作用
常見問題
Can I take Cisapride with Escitalopram?
MediHelp rates the interaction as contraindicated. Cisapride and Escitalopram are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Cisapride can cause dose-related torsades de pointes, and escitalopram also prolongs the QT interval in a dose-dependent fashion. The combination is contraindicated in the cisapride labelling.
How serious is the interaction between Cisapride and Escitalopram?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; use a prokinetic without QT effect or an alternative antidepressant.
What other medicines interact with Cisapride?
MediHelp also lists interactions of Cisapride with, for example, Apomorphine, Artemether, Azithromycin. The full list is on the Cisapride page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。