藥物交互作用
Citalopram + Escitalopram
嚴重程度: 禁忌併用
Citalopram and Escitalopram: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Escitalopram is the active S-enantiomer of citalopram, so this is therapeutic duplication. Together they produce additive serotonergic and QT-prolonging effects without added benefit.
用白話說明這項交互作用的意義
Citalopram and Escitalopram are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Citalopram belongs to Central Nervous System; Escitalopram belongs to Central Nervous System.
為什麼會發生
Duplicate SSRI activity leading to additive serotonin reuptake inhibition and QT prolongation.
處置方式
Do not use both together; select one agent. Switch directly or taper as appropriate and monitor for serotonin toxicity.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Citalopram 的其他交互作用
Escitalopram 的其他交互作用
常見問題
Can I take Citalopram with Escitalopram?
MediHelp rates the interaction as contraindicated. Citalopram and Escitalopram are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Escitalopram is the active S-enantiomer of citalopram, so this is therapeutic duplication. Together they produce additive serotonergic and QT-prolonging effects without added benefit.
How serious is the interaction between Citalopram and Escitalopram?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use both together; select one agent. Switch directly or taper as appropriate and monitor for serotonin toxicity.
What other medicines interact with Citalopram?
MediHelp also lists interactions of Citalopram with, for example, Cisapride, Dronedarone, Isocarboxazid. The full list is on the Citalopram page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
