藥物交互作用
Colestipol + Niacin
嚴重程度: 中度
Colestipol and Niacin: moderate interaction.
最後更新
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摘要
Colestipol is a bile acid sequestrant that can bind niacin in the gut and reduce how much is absorbed. This may blunt the lipid-lowering effect of niacin. The two are sometimes used together deliberately, so the practical effect is usually modest.
用白話說明這項交互作用的意義
Colestipol and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Colestipol belongs to Cardiovascular; Niacin belongs to Cardiovascular.
為什麼會發生
Colestipol binds niacin in the gastrointestinal lumen and reduces its oral absorption.
處置方式
Give niacin at least 1 hour before or 4 hours after colestipol. Monitor the lipid profile and adjust the niacin dose if the response is inadequate.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Niacin 的其他交互作用
Colestipol 的其他交互作用
常見問題
Can I take Colestipol with Niacin?
MediHelp rates the interaction as moderate. Colestipol and Niacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol is a bile acid sequestrant that can bind niacin in the gut and reduce how much is absorbed. This may blunt the lipid-lowering effect of niacin. The two are sometimes used together deliberately, so the practical effect is usually modest.
How serious is the interaction between Colestipol and Niacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give niacin at least 1 hour before or 4 hours after colestipol. Monitor the lipid profile and adjust the niacin dose if the response is inadequate.
What other medicines interact with Niacin?
MediHelp also lists interactions of Niacin with, for example, Alogliptin-metformin, Atorvastatin, Canagliflozin-metformin. The full list is on the Niacin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
