藥物交互作用
Cyclosporin + Flibanserin
嚴重程度: 禁忌併用
Cyclosporin and Flibanserin: contraindicated interaction.
最後更新
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摘要
Cyclosporine inhibits CYP3A4 and can increase flibanserin exposure. Raised flibanserin levels increase the risk of profound hypotension, syncope and CNS depression.
用白話說明這項交互作用的意義
Cyclosporin and Flibanserin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Cyclosporin belongs to Miscellaneous; Flibanserin belongs to Genitourinary.
為什麼會發生
CYP3A4 inhibition raises flibanserin exposure
處置方式
Do not use together; choose an alternative therapy.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Cyclosporin 的其他交互作用
Flibanserin 的其他交互作用
常見問題
Can I take Cyclosporin with Flibanserin?
MediHelp rates the interaction as contraindicated. Cyclosporin and Flibanserin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Cyclosporine inhibits CYP3A4 and can increase flibanserin exposure. Raised flibanserin levels increase the risk of profound hypotension, syncope and CNS depression.
How serious is the interaction between Cyclosporin and Flibanserin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; choose an alternative therapy.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。