藥物交互作用
Crizotinib + Flibanserin
嚴重程度: 禁忌併用
Crizotinib and Flibanserin: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Crizotinib is a moderate CYP3A4 inhibitor and can raise flibanserin exposure. Increased flibanserin levels risk severe hypotension, syncope and CNS depression.
用白話說明這項交互作用的意義
Crizotinib and Flibanserin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Crizotinib belongs to Oncology; Flibanserin belongs to Genitourinary.
為什麼會發生
CYP3A4 inhibition raises flibanserin exposure
處置方式
Do not use together; choose a different treatment and avoid for at least 2 days after stopping the inhibitor.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Flibanserin 的其他交互作用
Crizotinib 的其他交互作用
常見問題
Can I take Crizotinib with Flibanserin?
MediHelp rates the interaction as contraindicated. Crizotinib and Flibanserin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Crizotinib is a moderate CYP3A4 inhibitor and can raise flibanserin exposure. Increased flibanserin levels risk severe hypotension, syncope and CNS depression.
How serious is the interaction between Crizotinib and Flibanserin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; choose a different treatment and avoid for at least 2 days after stopping the inhibitor.
What other medicines interact with Flibanserin?
MediHelp also lists interactions of Flibanserin with, for example, Atazanavir, Ceritinib, Clarithromycin. The full list is on the Flibanserin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
