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Flibanserin

Flibanserin is a medicine in the class genitourinary. It is used for hypoactive sexual desire disorder.

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僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Genitourinary
常見劑型
錠劑
常見規格
100 mg
已知交互作用
278 (禁忌併用: 43 · 嚴重: 52 · 中度: 157 · 輕微: 26)
商品名
7
國家與市場
2

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Postsynaptic serotonin-1A (5HT-1A) receptor agonist and 5HT-2A receptor antagonist; also elicits moderate antagonist activities at the 5-HT2B, 5-HT2C, and dopamine D4 receptors.

成人常用劑量（仿單摘要）

Hypoactive Sexual Desire Disorder: 100 mg PO once daily at bedtime

僅摘錄仿單中第一行劑量說明；完整的劑量內容請見 App。

懷孕與哺乳

懷孕
Unknown No studies in pregnant women. In rats and rabbits, fetal harm occurred only at more than 15 times human exposure with maternal toxicity. It is for premenopausal women with low sexual desire; stop if pregnancy occurs.
哺乳
Unsafe Not known whether it passes into human milk; it does into rat milk. LactMed: high protein binding suggests low milk levels. US label: not recommended while breastfeeding because of possible serious effects, including sedation, in the infant.

已通報的副作用

  • Fatigue
  • Nausea
  • Insomnia
  • Somnolence
  • Dizziness

禁忌症

  • Coadministration with moderate or strong CYP3A4 inhibitors
  • Hepatic impairment
  • Known hypersensitivity to drug or excipients

哪些人需要特別留意

  • Coadministration with moderate or strong CYP3A4 inhibitors increases flibanserin concentrations, which can cause severe hypotension and syncope.
  • Hypersensitivity reactions, including anaphylaxis, reactions consistent with angioedema (eg, swelling of the face, lips, and mouth), pruritus, and urticaria reported.
  • Flibanserin may increase blood concentrations of P-gp substrates (eg, digoxin, sirolimus).

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。

重要交互作用 (278)

All 278 interactions, with severity and what to do

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解鎖完整頁面

建立帳號並開始 Pro+ 試用，即可開啟 Flibanserin 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。

  • Dosing by age, kidney and liver function, and further dose lines
  • Renal and hepatic dose adjustments
  • Paediatric dosing
  • Pharmacokinetics
  • Patient counselling points
  • Food interactions
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常見問題

What is Flibanserin used for?

Flibanserin is a medicine in the class genitourinary. It is used for Hypoactive sexual desire disorder.

What side effects have been reported with Flibanserin?

Fatigue, Nausea, Insomnia, Somnolence, Dizziness.

Can Flibanserin be taken in pregnancy or while breastfeeding?

Pregnancy: Unknown. No studies in pregnant women. In rats and rabbits, fetal harm occurred only at more than 15 times human exposure with maternal toxicity. It is for premenopausal women with low sexual desire; stop if pregnancy occurs. Breastfeeding: Unsafe. Not known whether it passes into human milk; it does into rat milk. LactMed: high protein binding suggests low milk levels. US label: not recommended while breastfeeding because of possible serious effects, including sedation, in the infant.

What does Flibanserin interact with?

MediHelp lists 278 known interactions for Flibanserin. Contraindicated: 43 · Major: 52 · Moderate: 157 · Minor: 26. The most serious include Atazanavir, Ceritinib, Clarithromycin.

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