藥物交互作用
Atazanavir + Flibanserin
嚴重程度: 禁忌併用
Atazanavir and Flibanserin: contraindicated interaction.
最後更新
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摘要
Atazanavir is a strong CYP3A4 inhibitor and markedly raises flibanserin concentrations. This can cause severe hypotension, syncope and profound sedation.
用白話說明這項交互作用的意義
Atazanavir and Flibanserin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Atazanavir belongs to Anti Virals; Flibanserin belongs to Genitourinary.
為什麼會發生
Inhibition of CYP3A4 metabolism of flibanserin increases its exposure.
處置方式
Do not coadminister. Avoid starting flibanserin until at least 2 weeks after stopping the inhibitor.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Flibanserin 的其他交互作用
Atazanavir 的其他交互作用
常見問題
Can I take Atazanavir with Flibanserin?
MediHelp rates the interaction as contraindicated. Atazanavir and Flibanserin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Atazanavir is a strong CYP3A4 inhibitor and markedly raises flibanserin concentrations. This can cause severe hypotension, syncope and profound sedation.
How serious is the interaction between Atazanavir and Flibanserin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not coadminister. Avoid starting flibanserin until at least 2 weeks after stopping the inhibitor.
What other medicines interact with Flibanserin?
MediHelp also lists interactions of Flibanserin with, for example, Ceritinib, Clarithromycin, Cobicistat. The full list is on the Flibanserin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
