藥物交互作用
Cyclosporin + Oritavancin
嚴重程度: 輕微
Cyclosporin and Oritavancin: minor interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Oritavancin is a weak CYP3A4 inducer and could slightly lower cyclosporine concentrations. Clinical significance is uncertain, but cyclosporine has a narrow therapeutic index so loss of immunosuppression is a theoretical concern.
用白話說明這項交互作用的意義
Cyclosporin and Oritavancin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cyclosporin belongs to Miscellaneous; Oritavancin belongs to Anti Bacterial.
為什麼會發生
Weak induction of CYP3A4 by oritavancin may modestly increase cyclosporine metabolism.
處置方式
Check cyclosporine trough concentrations during and shortly after oritavancin treatment. Adjust the dose only if levels fall below target.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Cyclosporin 的其他交互作用
Oritavancin 的其他交互作用
常見問題
Can I take Cyclosporin with Oritavancin?
MediHelp rates the interaction as minor. Cyclosporin and Oritavancin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oritavancin is a weak CYP3A4 inducer and could slightly lower cyclosporine concentrations. Clinical significance is uncertain, but cyclosporine has a narrow therapeutic index so loss of immunosuppression is a theoretical concern.
How serious is the interaction between Cyclosporin and Oritavancin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check cyclosporine trough concentrations during and shortly after oritavancin treatment. Adjust the dose only if levels fall below target.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。