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藥物交互作用

Cyclosporin + Oritavancin

嚴重程度: 輕微

Cyclosporin and Oritavancin: minor interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Oritavancin is a weak CYP3A4 inducer and could slightly lower cyclosporine concentrations. Clinical significance is uncertain, but cyclosporine has a narrow therapeutic index so loss of immunosuppression is a theoretical concern.

用白話說明這項交互作用的意義

Cyclosporin and Oritavancin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Cyclosporin belongs to Miscellaneous; Oritavancin belongs to Anti Bacterial.

證據等級: Low

為什麼會發生

Weak induction of CYP3A4 by oritavancin may modestly increase cyclosporine metabolism.

處置方式

Check cyclosporine trough concentrations during and shortly after oritavancin treatment. Adjust the dose only if levels fall below target.

可向藥師詢問的問題

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Cyclosporin 與 Oritavancin 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Cyclosporin with Oritavancin?

MediHelp rates the interaction as minor. Cyclosporin and Oritavancin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oritavancin is a weak CYP3A4 inducer and could slightly lower cyclosporine concentrations. Clinical significance is uncertain, but cyclosporine has a narrow therapeutic index so loss of immunosuppression is a theoretical concern.

How serious is the interaction between Cyclosporin and Oritavancin?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check cyclosporine trough concentrations during and shortly after oritavancin treatment. Adjust the dose only if levels fall below target.

What other medicines interact with Cyclosporin?

MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.

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