藥物交互作用
Cyclosporin + Ublituximab
嚴重程度: 嚴重
Cyclosporin and Ublituximab: major interaction.
最後更新
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摘要
Ublituximab depletes B cells and cyclosporine suppresses T cells, so together they raise the risk of serious infections. Effects of ublituximab persist for months after dosing.
用白話說明這項交互作用的意義
Cyclosporin and Ublituximab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cyclosporin belongs to Miscellaneous; Ublituximab belongs to Miscellaneous.
為什麼會發生
Additive immunosuppression from anti-CD20 B-cell depletion and calcineurin inhibition.
處置方式
Avoid combining unless clearly needed; if used, monitor closely for infection and consider prophylaxis and the prolonged duration of B-cell depletion.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Cyclosporin 的其他交互作用
Ublituximab 的其他交互作用
常見問題
Can I take Cyclosporin with Ublituximab?
MediHelp rates the interaction as major. Cyclosporin and Ublituximab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ublituximab depletes B cells and cyclosporine suppresses T cells, so together they raise the risk of serious infections. Effects of ublituximab persist for months after dosing.
How serious is the interaction between Cyclosporin and Ublituximab?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining unless clearly needed; if used, monitor closely for infection and consider prophylaxis and the prolonged duration of B-cell depletion.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
