藥物交互作用
Fingolimod + Ublituximab
嚴重程度: 嚴重
Fingolimod and Ublituximab: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Ublituximab depletes B cells for a prolonged period and fingolimod reduces circulating lymphocytes. Combined or sequential use may increase the risk of serious infection.
用白話說明這項交互作用的意義
Fingolimod and Ublituximab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Fingolimod belongs to Central Nervous System; Ublituximab belongs to Miscellaneous.
為什麼會發生
Additive immunosuppression through B-cell depletion and lymphocyte sequestration.
處置方式
Avoid concurrent use. When switching between them, account for the prolonged effect of ublituximab and monitor lymphocyte counts and infections.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Fingolimod 的其他交互作用
Ublituximab 的其他交互作用
常見問題
Can I take Fingolimod with Ublituximab?
MediHelp rates the interaction as major. Fingolimod and Ublituximab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ublituximab depletes B cells for a prolonged period and fingolimod reduces circulating lymphocytes. Combined or sequential use may increase the risk of serious infection.
How serious is the interaction between Fingolimod and Ublituximab?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use. When switching between them, account for the prolonged effect of ublituximab and monitor lymphocyte counts and infections.
What other medicines interact with Fingolimod?
MediHelp also lists interactions of Fingolimod with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Pimozide. The full list is on the Fingolimod page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
