藥物交互作用
Dalteparin + Ketorolac
嚴重程度: 禁忌併用
Dalteparin and Ketorolac: contraindicated interaction.
最後更新
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摘要
Ketorolac impairs platelet function and can cause GI bleeding, and dalteparin is an anticoagulant, so serious hemorrhage risk increases, including spinal or epidural hematoma around neuraxial procedures. Ketorolac labeling contraindicates use in patients at risk of bleeding.
用白話說明這項交互作用的意義
Dalteparin and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dalteparin belongs to Cardiovascular; Ketorolac belongs to Musculoskeletal.
為什麼會發生
Additive hemostatic impairment through antiplatelet NSAID effect and factor Xa inhibition by low molecular weight heparin.
處置方式
Avoid ketorolac in patients on dalteparin and select a non-NSAID analgesic; if exposure occurs, monitor for bleeding signs and hemoglobin.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Ketorolac 的其他交互作用
Dalteparin 的其他交互作用
常見問題
Can I take Dalteparin with Ketorolac?
MediHelp rates the interaction as contraindicated. Dalteparin and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac impairs platelet function and can cause GI bleeding, and dalteparin is an anticoagulant, so serious hemorrhage risk increases, including spinal or epidural hematoma around neuraxial procedures. Ketorolac labeling contraindicates use in patients at risk of bleeding.
How serious is the interaction between Dalteparin and Ketorolac?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ketorolac in patients on dalteparin and select a non-NSAID analgesic; if exposure occurs, monitor for bleeding signs and hemoglobin.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
