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藥物交互作用

Dapagliflozin-metformin + Lonapegsomatropin

嚴重程度: 中度

Dapagliflozin-metformin and Lonapegsomatropin: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Growth hormone can reduce insulin sensitivity and raise blood glucose, particularly at higher doses. Patients with diabetes may need more antihyperglycemic therapy after starting it.

用白話說明這項交互作用的意義

Dapagliflozin-metformin and Lonapegsomatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Dapagliflozin-metformin belongs to Endocrine; Lonapegsomatropin belongs to Endocrine.

證據等級: Moderate

為什麼會發生

Growth hormone induces insulin resistance and increases hepatic glucose output and lipolysis.

處置方式

Monitor blood glucose closely when starting or adjusting lonapegsomatropin and adjust antidiabetic doses as required.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Additional notes
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  • Interaction checker for a whole prescription

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常見問題

Can I take Dapagliflozin-metformin with Lonapegsomatropin?

MediHelp rates the interaction as moderate. Dapagliflozin-metformin and Lonapegsomatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Growth hormone can reduce insulin sensitivity and raise blood glucose, particularly at higher doses. Patients with diabetes may need more antihyperglycemic therapy after starting it.

How serious is the interaction between Dapagliflozin-metformin and Lonapegsomatropin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose closely when starting or adjusting lonapegsomatropin and adjust antidiabetic doses as required.

What other medicines interact with Dapagliflozin-metformin?

MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.

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