藥物交互作用
Deferasirox + Prasugrel
嚴重程度: 嚴重
Deferasirox and Prasugrel: major interaction.
最後更新
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摘要
Deferasirox can cause GI ulceration and hemorrhage, and prasugrel potently inhibits platelet aggregation. Together they markedly raise the risk of serious GI bleeding.
用白話說明這項交互作用的意義
Deferasirox and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Deferasirox belongs to Miscellaneous; Prasugrel belongs to Cardiovascular.
為什麼會發生
Additive bleeding risk from deferasirox mucosal injury and irreversible P2Y12 platelet inhibition.
處置方式
Monitor for GI bleeding and hemoglobin, consider gastroprotection with a proton pump inhibitor, and reassess the need for both drugs in patients with bleeding risk.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Deferasirox 的其他交互作用
Prasugrel 的其他交互作用
常見問題
Can I take Deferasirox with Prasugrel?
MediHelp rates the interaction as major. Deferasirox and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Deferasirox can cause GI ulceration and hemorrhage, and prasugrel potently inhibits platelet aggregation. Together they markedly raise the risk of serious GI bleeding.
How serious is the interaction between Deferasirox and Prasugrel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for GI bleeding and hemoglobin, consider gastroprotection with a proton pump inhibitor, and reassess the need for both drugs in patients with bleeding risk.
What other medicines interact with Deferasirox?
MediHelp also lists interactions of Deferasirox with, for example, Acetylsalicylic acid, Alosetron, Aluminum hydroxide. The full list is on the Deferasirox page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
