藥物交互作用
Apixaban + Prasugrel
嚴重程度: 嚴重
Apixaban and Prasugrel: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Prasugrel is a potent antiplatelet and apixaban is an anticoagulant. Together they substantially increase the risk of major bleeding.
用白話說明這項交互作用的意義
Apixaban and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Apixaban belongs to Cardiovascular; Prasugrel belongs to Cardiovascular.
為什麼會發生
Additive hemostatic impairment from irreversible P2Y12 inhibition and factor Xa inhibition.
處置方式
Avoid unless clearly indicated. In patients needing both, clopidogrel is generally preferred with an anticoagulant.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Apixaban 的其他交互作用
Prasugrel 的其他交互作用
常見問題
Can I take Apixaban with Prasugrel?
MediHelp rates the interaction as major. Apixaban and Prasugrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Prasugrel is a potent antiplatelet and apixaban is an anticoagulant. Together they substantially increase the risk of major bleeding.
How serious is the interaction between Apixaban and Prasugrel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unless clearly indicated. In patients needing both, clopidogrel is generally preferred with an anticoagulant.
What other medicines interact with Apixaban?
MediHelp also lists interactions of Apixaban with, for example, Dabigatran, Defibrotide, Edoxaban. The full list is on the Apixaban page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
