藥物交互作用
Deflazacort + Sorbitol
嚴重程度: 中度
Deflazacort and Sorbitol: moderate interaction.
最後更新
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摘要
Sorbitol has an osmotic laxative effect that can cause diarrhea and intestinal potassium loss, and deflazacort, a corticosteroid, can promote renal potassium excretion. Combined use may contribute to hypokalemia, mainly with repeated or large laxative doses.
用白話說明這項交互作用的意義
Deflazacort and Sorbitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deflazacort belongs to Miscellaneous; Sorbitol belongs to Gastrointestinal Tract.
為什麼會發生
Additive potassium loss from osmotic diarrhea and corticosteroid mineralocorticoid-related kaliuresis.
處置方式
Monitor serum potassium if sorbitol is used repeatedly or in large amounts with deflazacort. Replace potassium as needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Sorbitol 的其他交互作用
Deflazacort 的其他交互作用
- Adenovirus types 4 and 7 live + Deflazacort 禁忌併用
- Bcg vaccine live + Deflazacort 禁忌併用
- Deflazacort + Influenza virus vaccine quadrivalent intranasal 禁忌併用
- Deflazacort + Measles mumps and rubella vaccine 禁忌併用
- Deflazacort + Measles mumps and rubella vaccine live 禁忌併用
- Deflazacort + Measles mumps rubella and varicella vaccine live 禁忌併用
常見問題
Can I take Deflazacort with Sorbitol?
MediHelp rates the interaction as moderate. Deflazacort and Sorbitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sorbitol has an osmotic laxative effect that can cause diarrhea and intestinal potassium loss, and deflazacort, a corticosteroid, can promote renal potassium excretion. Combined use may contribute to hypokalemia, mainly with repeated or large laxative doses.
How serious is the interaction between Deflazacort and Sorbitol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium if sorbitol is used repeatedly or in large amounts with deflazacort. Replace potassium as needed.
What other medicines interact with Sorbitol?
MediHelp also lists interactions of Sorbitol with, for example, Sodium polystyrene sulfonate, Lamivudine. The full list is on the Sorbitol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
