藥物交互作用
Dexlansoprazole + Itraconazole
嚴重程度: 嚴重
Dexlansoprazole and Itraconazole: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Acid suppression lowers absorption of itraconazole capsules, risking subtherapeutic antifungal levels and treatment failure.
用白話說明這項交互作用的意義
Dexlansoprazole and Itraconazole can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dexlansoprazole belongs to Gastrointestinal Tract; Itraconazole belongs to Anti Fungals.
為什麼會發生
Raised gastric pH decreases dissolution and absorption of itraconazole capsules.
處置方式
Avoid with itraconazole capsules or use the oral solution. Monitor itraconazole levels and clinical response.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Dexlansoprazole 的其他交互作用
Itraconazole 的其他交互作用
常見問題
Can I take Dexlansoprazole with Itraconazole?
MediHelp rates the interaction as major. Dexlansoprazole and Itraconazole can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Acid suppression lowers absorption of itraconazole capsules, risking subtherapeutic antifungal levels and treatment failure.
How serious is the interaction between Dexlansoprazole and Itraconazole?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid with itraconazole capsules or use the oral solution. Monitor itraconazole levels and clinical response.
What other medicines interact with Dexlansoprazole?
MediHelp also lists interactions of Dexlansoprazole with, for example, Mavacamten, Rilpivirine, Acalabrutinib. The full list is on the Dexlansoprazole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
