藥品參考
Dexlansoprazole
Dexlansoprazole is a medicine in the class gastrointestinal tract. It is used for gerd.
- 藥物類別: Gastrointestinal Tract
- 用途: gerd
最後更新
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Gastrointestinal Tract
- 常見劑型
- 膠囊
- 常見規格
- 60 mg, 30 mg
- 已知交互作用
- 116 (禁忌併用: 2 · 嚴重: 18 · 中度: 46 · 輕微: 50)
- 商品名
- 22
- 國家與市場
- 4
用途
作用方式
R-enantiomer of lansoprazole; PPI; binds to H+/K+-exchanging ATPase (proton pump) in gastric parietal cells, resulting in blockage of acid secretion, Dual release formulation, Relative Potency: not available.
成人常用劑量（仿單摘要）
General dosing: 30-60 mg orally every day for up to 8 weeks.
一般服用方式
Proton pump inhibitors are usually taken by mouth once a day, often before a meal, for a course whose length depends on the reason for treatment.
懷孕與哺乳
- 懷孕
- Safe No human studies, but data for lansoprazole, of which it is an enantiomer, show no harm in pregnancy. Acceptable when a PPI is needed; omeprazole has the most pregnancy data.
- 哺乳
- Safe No milk data. LactMed: as lansoprazole has been used safely in newborns, the amount in milk is unlikely to harm the infant. Acceptable.
已通報的副作用
- Vomiting
- Diarrhea
- Nausea
- Abdominal pain
- URI
禁忌症
- Hypersensitivity reactions, including anaphylaxis and acute interstitial nephritis reported
- PPIs are contraindicated with rilpivirine-containing products
哪些人需要特別留意
- Proton pump inhibitors (PPIs) are possibly associated with increased incidence of Clostridium difficile-associated diarrhea (CDAD).
- PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist, particularly with prolonged (>1 yr), high-dose therapy.
- Daily long-term use (e.g., longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin.
People taking proton pump inhibitors for a long time should have the need for treatment reviewed, because long-term use is linked to low magnesium, vitamin B12 deficiency, bone fractures and gut infections. Tell your pharmacist about all other medicines, since some interact.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (116)
- Dexlansoprazole + Mavacamten Contraindicated
- Dexlansoprazole + Rilpivirine Contraindicated
- Acalabrutinib + Dexlansoprazole Major
- Atazanavir + Dexlansoprazole Major
- Dacomitinib + Dexlansoprazole Major
- Dasatinib + Dexlansoprazole Major
- Dexlansoprazole + Erlotinib Major
- Dexlansoprazole + Gefitinib Major
- Dexlansoprazole + Infigratinib Major
- Dexlansoprazole + Itraconazole Major
同類別的其他藥品
常見問題
What is Dexlansoprazole used for?
Dexlansoprazole is a medicine in the class gastrointestinal tract. It is used for GERD, Peptic ulcer.
What side effects have been reported with Dexlansoprazole?
Vomiting, Diarrhea, Nausea, Abdominal pain, URI.
Can Dexlansoprazole be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. No human studies, but data for lansoprazole, of which it is an enantiomer, show no harm in pregnancy. Acceptable when a PPI is needed; omeprazole has the most pregnancy data. Breastfeeding: Safe. No milk data. LactMed: as lansoprazole has been used safely in newborns, the amount in milk is unlikely to harm the infant. Acceptable.
What does Dexlansoprazole interact with?
MediHelp lists 116 known interactions for Dexlansoprazole. Contraindicated: 2 · Major: 18 · Moderate: 46 · Minor: 50. The most serious include Mavacamten, Rilpivirine, Acalabrutinib.
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