藥物交互作用
Digoxin + Senna
嚴重程度: 中度
Digoxin and Senna: moderate interaction.
最後更新
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摘要
Prolonged or excessive senna use can cause diarrhea and potassium loss. Hypokalemia makes the heart more sensitive to digoxin and raises the risk of arrhythmias and digoxin toxicity.
用白話說明這項交互作用的意義
Digoxin and Senna can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Digoxin belongs to Cardiovascular; Senna belongs to Gastrointestinal Tract.
為什麼會發生
Laxative-induced gastrointestinal potassium loss produces hypokalemia, which enhances digoxin's cardiac toxicity.
處置方式
Avoid prolonged senna use, and monitor serum potassium and magnesium in patients using it regularly. Correct electrolyte deficits and watch for signs of digoxin toxicity.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Digoxin 的其他交互作用
Senna 的其他交互作用
常見問題
Can I take Digoxin with Senna?
MediHelp rates the interaction as moderate. Digoxin and Senna can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Prolonged or excessive senna use can cause diarrhea and potassium loss. Hypokalemia makes the heart more sensitive to digoxin and raises the risk of arrhythmias and digoxin toxicity.
How serious is the interaction between Digoxin and Senna?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid prolonged senna use, and monitor serum potassium and magnesium in patients using it regularly. Correct electrolyte deficits and watch for signs of digoxin toxicity.
What other medicines interact with Digoxin?
MediHelp also lists interactions of Digoxin with, for example, Lily of the valley, Squill, Adagrasib. The full list is on the Digoxin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
