藥物交互作用
Digoxin + Squill
嚴重程度: 禁忌併用
Digoxin and Squill: contraindicated interaction.
最後更新
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摘要
Squill contains cardiac glycosides (scilliroside-type bufadienolides) with digoxin-like activity. Combined use produces additive effects and a high risk of digitalis toxicity, including arrhythmias, nausea and visual disturbances.
用白話說明這項交互作用的意義
Digoxin and Squill are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Additive inhibition of Na+/K+-ATPase from the glycosides in squill and digoxin.
處置方式
Avoid squill in patients taking digoxin. If exposure has occurred, check digoxin level, potassium and ECG.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Digoxin 的其他交互作用
常見問題
Can I take Digoxin with Squill?
MediHelp rates the interaction as contraindicated. Digoxin and Squill are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Squill contains cardiac glycosides (scilliroside-type bufadienolides) with digoxin-like activity. Combined use produces additive effects and a high risk of digitalis toxicity, including arrhythmias, nausea and visual disturbances.
How serious is the interaction between Digoxin and Squill?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid squill in patients taking digoxin. If exposure has occurred, check digoxin level, potassium and ECG.
What other medicines interact with Digoxin?
MediHelp also lists interactions of Digoxin with, for example, Lily of the valley, Adagrasib, Amiodarone. The full list is on the Digoxin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
