藥物交互作用
Dipyridamole + Regadenoson
嚴重程度: 嚴重
Dipyridamole and Regadenoson: major interaction.
最後更新
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摘要
Dipyridamole inhibits cellular adenosine uptake and deamination, which can potentiate adenosine receptor-mediated effects and alter the response to the A2A agonist regadenoson during myocardial perfusion imaging. The result may be unpredictable vasodilation, hypotension or altered test performance.
用白話說明這項交互作用的意義
Dipyridamole and Regadenoson can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dipyridamole belongs to Cardiovascular; Regadenoson belongs to Cardiovascular.
為什麼會發生
Dipyridamole raises adenosine levels and alters adenosine receptor signaling, so the pharmacodynamic response to regadenoson is unpredictable.
處置方式
Withhold dipyridamole for at least 2 days before regadenoson stress testing, as recommended in labeling. Monitor blood pressure and ECG during the procedure if exposure cannot be avoided.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Dipyridamole 的其他交互作用
Regadenoson 的其他交互作用
常見問題
Can I take Dipyridamole with Regadenoson?
MediHelp rates the interaction as major. Dipyridamole and Regadenoson can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dipyridamole inhibits cellular adenosine uptake and deamination, which can potentiate adenosine receptor-mediated effects and alter the response to the A2A agonist regadenoson during myocardial perfusion imaging. The result may be unpredictable vasodilation, hypotension or altered test performance.
How serious is the interaction between Dipyridamole and Regadenoson?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Withhold dipyridamole for at least 2 days before regadenoson stress testing, as recommended in labeling. Monitor blood pressure and ECG during the procedure if exposure cannot be avoided.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
