藥物交互作用
Betrixaban + Dipyridamole
嚴重程度: 嚴重
Betrixaban and Dipyridamole: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Dipyridamole inhibits P-glycoprotein and may increase betrixaban exposure. Together with the additive antiplatelet and anticoagulant effects, bleeding risk rises.
用白話說明這項交互作用的意義
Betrixaban and Dipyridamole can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
P-glycoprotein inhibition by dipyridamole increases betrixaban levels, plus additive effects on hemostasis.
處置方式
Reduce betrixaban to the labeled P-gp inhibitor dose of 80 mg once then 40 mg daily. Monitor for bleeding.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Dipyridamole 的其他交互作用
常見問題
Can I take Betrixaban with Dipyridamole?
MediHelp rates the interaction as major. Betrixaban and Dipyridamole can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dipyridamole inhibits P-glycoprotein and may increase betrixaban exposure. Together with the additive antiplatelet and anticoagulant effects, bleeding risk rises.
How serious is the interaction between Betrixaban and Dipyridamole?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Reduce betrixaban to the labeled P-gp inhibitor dose of 80 mg once then 40 mg daily. Monitor for bleeding.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Dabigatran. The full list is on the Dipyridamole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
