藥物交互作用
Dipyridamole + Riociguat
嚴重程度: 禁忌併用
Dipyridamole and Riociguat: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Riociguat labeling contraindicates nonspecific PDE inhibitors such as dipyridamole because they can potentiate cGMP-mediated vasodilation. This may cause marked hypotension and syncope.
用白話說明這項交互作用的意義
Dipyridamole and Riociguat are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dipyridamole belongs to Cardiovascular; Riociguat belongs to Cardiovascular.
為什麼會發生
Dipyridamole inhibits phosphodiesterases and adenosine uptake, augmenting cGMP-mediated vasodilation stimulated by riociguat.
處置方式
Do not coadminister; use an alternative antiplatelet agent in patients on riociguat.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Dipyridamole 的其他交互作用
Riociguat 的其他交互作用
常見問題
Can I take Dipyridamole with Riociguat?
MediHelp rates the interaction as contraindicated. Dipyridamole and Riociguat are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Riociguat labeling contraindicates nonspecific PDE inhibitors such as dipyridamole because they can potentiate cGMP-mediated vasodilation. This may cause marked hypotension and syncope.
How serious is the interaction between Dipyridamole and Riociguat?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not coadminister; use an alternative antiplatelet agent in patients on riociguat.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Adenosine, Betrixaban, Dabigatran. The full list is on the Dipyridamole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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